Quarterly report pursuant to Section 13 or 15(d)

Stock-based Compensation - Schedule of stock-based compensation expense (Details)

v3.22.2.2
Stock-based Compensation - Schedule of stock-based compensation expense (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based compensation expense $ 19,500 $ 19,100 $ 60,900 $ 89,700
Research and Development Expense        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based compensation expense 8,200 5,800 23,400 22,600
Selling, General and Administrative Expenses        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Share-based compensation expense $ 11,300 $ 13,300 $ 37,500 $ 67,100